NIHR Oxford Health Clinical Research Facility
Improving mental and cognitive health treatments through clinical research
NIHR Oxford BRC Statistics Hub Lunchtime Seminar: Multilevel modelling in clinical trials
Wednesday 9th April at 1:00 pm – 1:30 pm
Oxford Health BRC colleagues are welcome to join this lunchtime seminar, organised by the NIHR Oxford BRC Statistics Hub.
The seminar is part of a series. Each seminar is 20 minutes long followed by 10 minutes of Q&A, and will be held via Microsoft Teams.
Multilevel modelling in clinical trials
Dr Daphne Kounali, OCTRU Lead Statistician
Wednesday 9th April 2025, 1:00-1:30pm
A multilevel model is a statistical tool used to analyze data with a complex dependence structure, such as when patients are nested within hospitals or when there are multiple levels of treatment providers and geographic locations. In this seminar, I will define the different types of structures in clinical trials and discuss various applications of multilevel models, including incorporating repeated measurements, accounting for drop-out, and addressing measurement error. I will demonstrate how realistic assumptions and focusing on structure can help understand contextual effects and heterogeneity in outcomes, providing more precise estimates of treatment effects and predictions.
No registration is required.
Click here to join the session.